Jpn J Pharmacol 69(2) 1995


Regular Papers

Page 75
Structure-activity relationships of alkylxanthines: Alkyl chain elongation at the N1- or N7-position decreases cardiotonic activity in the isolated guinea pig heart
Fujiko Sanae, Shinji Ohmae, Mariko Kurita, Hiroyuki Sawanishi, Kenzo Takagi and Ken-ichi Miyamoto

Page 83
Inhibition of cocaine sensitization by MK-801, a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist: Evaluation by ambulatory activity in mice
Iturou Ida, Takayasu Asami and Hisashi Kuribara

Page 91
Antisecretory effect of leminoprazole on histamine-stimulated gastric acid secretion in dogs: Potent local effect
Susumu Okabe, Kenichi Shimosako and Hiroyuki Harada

Page 101
Effects of efonidipine hydrochloride on cholesterol esterification mediated by beta-very low density lipoprotein in J774 macrophages
Masaki Kitahara, Kyomi Toyada, Toshie Yamashita, Mitsuaki Sakashita, Sakuya Tanaka and Yasushi Saito

Page 111
Difference among angiotensin-converting enzyme inhibitors in potentiating effects on bradykinin-induced microvascular leakage in guinea pig airways
Takashi Murata, Yukio Matsumoto, Tatsuo Kashida, Osamu Kaminuma, Kazuaki Naito, Katsuo Ikezawa and Kei Tsuzurahara

Page 119
Inhibitory effect of cilnidipine on pressor response to acute cold stress in spontaneously hypertensive rats
Masahiro Hosono, Tohru Hiruma, Kiyoshi Watanabe, Yutaka Hayashi, Haruo Ohnishi, Yoshinobu Takata and Hitoshi Kato

Page 127
Inhibitory effect of cilnidipine on vascular sympathetic neurotransmission and subsequent vasoconstriction in spontaneously hypertensive rats
Masahiro Hosono, Shigeo Fujii, Tohru Hiruma, Kiyoshi Watanabe, Yutaka Hayashi, Haruo Ohnishi, Yoshinobu Takata and Hitoshi Kato

Page 135
Effects of folic acid and pyrimethamine, a dihydrofolate reductase inhibitor, on intestinal absorption of folates in rats
Gen Kudo, Naofumi Ohgushi, Minoru Shimoda and Ei-ichi Kokue

Page 143
Effect of argatroban on microthrombi formation and brain damage in the rat middle cerebral artery thrombosis model
Hiroshi Kawai, Kazuo Umemura and Mitsuyoshi Nakashima

Page 149
Increase in vascular sensitivity to angiotensin II and norepinephrine after four-day infusion of 0.3 M sodium chloride in conscious kininogen-deficient Brown Norway Katholiek rats
Masataka Majima, Keiichi Adachi, Yoshikazu Kuribayashi, Susumu Mizogami and Makoto Katori

Page 159
Role of the steady-state Na+ channel current in pacemaker depolarizations in young embryonic chick ventricular myocytes
Hideaki Sada, Takashi Ban, Takeshi Fujita, Yoshio Ebina and Nicholas Sperelakis

Short Communications

Page 167
The release and subsequent synthesis of histamine in a transfected subclone of rat basophilic leukemia cells that expresses human muscarinic m1 receptors
Yoshinori Goto and Kazutaka Maeyama

Page 173
Metabolic effects of glibenclamide in isolated rat hepatocytes in the absence of extracellular Ca2+
Takahide Nomura, Masatsugu Ohtsuki, Toshiko Watanabe, Seiko Hasegawa, Shigeru Matsui, Akira Tomita, Chiho Sumi-Ichinose, Hiroko Nomura and Yasumichi Hagino

Page 177
Hypotensive and bradycardic effects of dl-tetrahydropalmatine mediated by decrease in hypothalamic serotonin release in the rat
Fu-Yu Chueh, Ming-Tsuen Hsieh, Chieh-Fu Chen and Mao-Tsun Lin


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