Jpn J Pharmacol 81 (1) 1999


Review

1 - 6
-Current Perspective-
Contribution of Glutamate Receptors to Benzodiazepins Withdrawal Signs

Makoto Tsuda, Norifumi Shimizu and Tsutomu Suzuki

Full Papers

7 - 11
Antioxidant Action of the Antiarrhythmic Drug Mexiletine in Brain Membranes
Ediz Demirpece, Hakan Caner, Murat Bavbek and Kamer Kilinc

12 - 20
Analysis of Domain Responsible for Desensitization of E´?1-Adrenergic Receptor
Chiyuki Akiyama, Taku Nagao and Hitoshi Kurose

21 - 28
ATZ1993, an Orally Active and Novel Nonpeptide Antagonist for Endothelin Receptors and Inhibition of Intimal Hyperplasia After Balloon Denudation of the Rabbit Carotid Artery
Hiroshi Azuma, Jun Sato, Hiroshi Masuda, Moritaka Goto, Satoru Tamaoki, Akiko Sugimoto, Hidehisa Hamasaki and Haruo Yamashita

29 - 33
Melatonin Inhibits the Central Sympatho-adrenomedullary Outflow in Rats
Muchun Wang, Kunihiko Yokotani, Kumiko Nakamura, Yoshinori Murakami,
Shoshiro Okada and Yoshitsugu Osumi

34 - 37
Antinociceptive Effect of R-(+)-Hyoscyamine on the Conjunctival Reflex Test in Rabbits
Carla Ghelardini, Nicoletta Galeotti, Lia Fantetti, Fulvio Gualtieri,
Serena Scapecchi and Alessandro Bartolini

38 - 47
6-Hydroxydopamine Induced Cardiac Malformations and Alterations
of the Autonomic Nervous System in the Developing Chicken Embryo

Andrew K.S. Ho, Richard McLaughlin, Albert Chan and Rose Duffield

48 - 55
Repeated Antigen Inhalations Alter Chemical Mediators That Cause Asthmatic Obstruction in Guinea Pigs
Kazunori Yamashita, Takeshi Nabe, Hisao Tomioka and Shigekatsu Kohno

56 - 62
Metabolites of Isopropyl Unoprostone as Potential Ophthalmic Solutions to Reduce Intraocular Pressure in Pigmented Rabbits
Kenji Kashiwagi, Yoko Iizuka and Shigeo Tsukahara

63 - 72
Comparative Study of TA-606, a Novel Angiotensin II Receptor Antagonist, With Losartan in Terms of Species Difference and Orthostatic Hypotension
Yoshihiro Hashimoto, Rikiya Ohashi, Koichi Minami and Hiroshi Narita

73 - 78
Recombinant E1-Deleted Adenoviral Vectors Induce Apoptosis in a Rat Airway Epithelial Mucous Goblet Cell Line
Shinji Teramoto, Takeshi Matsuse, Hirotoshi Matsui, Eijiro Ohga, Takeo Ishii, Takahide Nagase and Yasuyoshi Ouchi

79 - 85
Effects of a Class III Antiarrhythmic Drug, Dofetilide, on the In Situ
Canine Heart Assessed by the Simultaneous Monitoring of Hemodynamic and Electrophysiological Parameters

Yoshioki Satoh, Atsushi Sugiyama, Kohji Tamura and Keitaro Hashimoto

86 - 93
Rat Gastric Mucous Gel Layer Contains Sialomucin Not Produced by the Stomach
Hisamasa Kodaira, Kazuhiko Ishihara, Kyoko Hotta, Masatoyo Kagoshima, Hideyo Shimada and Kunio Ishii

94 - 98
The Profile of FR140423, a Novel Anti-inflammatory Compound, in Yeast-Induced Rat Hyperalgesia
Takehiro Ochi, Takashi Fujii, Yukio Motoyama and Toshio Goto

99 - 106
Mechanism of Structural Remodelling of the Rat Aorta
During Long-Term NG-Nitro-l-arginine Methyl Ester Treatment
Iveta Bernatova, Ol'ga Pechanova and Frantisek Kristek

107 - 114
Vasodilating Effect and Tissue Accumulation of Prostaglandin E1
Incorporated in Lipid Microspheres on the Rat Ductus Arteriosus

Yukihiro Chino, Toshiya Minagawa, Yoshiro Kohno, Kiyomi Fukushima and Kazuo Momma

115 - 121
The Inhibition of Monoamine Oxidase Activity by Various Antidepressants: Differences Found in Various Mammalian Species
Toru Egashira, Fusako Takayama and Yasumitsu Yamanaka


Short Communication

122 - 124
Diazepam Increases Calcium Sensitivity of the Skinned Cardiac Muscle Fiber in Guinea Pig
Yukio Hara, Akihito Chugun, Keisuke Futamura, Takeshi Nishino and Hiroshi Kondo


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