公益社団法人日本薬理学会

The Japanese Pharmacological Society

JPS Prize

The JPS Prize 2023 Awards

• Estrogen decline is a risk factor for paclitaxel-induced peripheral neuropathy: Clinical evidence supported by a preclinical study
  Tomoyoshi Miyamoto, Shiori Hiramoto, Ayano Kanto, Maho Tsubota, Masanori Fujitani, Hiroki Fukuyama, Shigekatsu Hatanaka, Fumiko Sekiguchi, Yuichi Koizumi, Atsufumi Kawabata.
  Journal of Pharmacological Sciences, Volume 146, Issue 1, May 2021, Pages 49-57.
  Doi: 10.1016/j.jphs.2021.03.001

第28回JPS優秀論文賞受賞論文プロフィール

The JPS Prize 2022 Awards

• Boron delivery for boron neutron capture therapy targeting a cancer-upregulated oligopeptide transporter.
  Junji Miyabe, Ryuichi Ohgaki, Keijiro Saito, Ling Wei, Lili Quan, Chunhuan Jin, Xingming Liu, Suguru Okuda, Shushi Nagamori, Hiroshi Ohki, Kazuo Yoshino, Hidenori Inohara, Yoshikatsu Kanai.
  Journal of Pharmacological Sciences, Volume 139, Issue 3, 2019, Pages 215-222.
  Doi:10.1016/j.jphs.2019.01.012
• Pretreatment with KGA-2727, a selective SGLT1 inhibitor, is protective against myocardial infarction-induced ventricular remodeling and heart failure in mice.
  Yohei Sawa, Maki Saito, Nanae Ishida, Miho Ibi, Naoko Matsushita, Yoshihiro Morino, Eiichi Taira, Masamichi Hirose.
  Journal of Pharmacological Sciences, Volume 142, Issue 1, 2020, Pages 16-25.
  Doi:10.1016/j.jphs.2019.11.001.

第27回JPS優秀論文賞受賞論文プロフィール

The JPS Prize 2021 Awards

• Neuropeptide oxytocin enhances μ opioid receptor signaling as a positive allosteric modulator
  Yoshiyuki Meguro, Kanako Miyano, Shigeto Hirayama, Yuki Yoshida, Naoto Ishibashi, Takumi Ogino, Yuriko Fujii, Sei Manabe, Moeko Eto, Miki Nonaka, Hideaki Fujii, Yoichi Ueta, Minoru Narita, Naohiro Sata, Toshihiko Yada, Yasuhito Uezono
  Division of Cancer Pathophysiology, National Cancer Center Research Institute, Tokyo, Japan
  Vol. 137, No.1, pp. 67-75 (2018)

第26回JPS優秀論文賞受賞論文プロフィール

The JPS Prize 2020 Awards

• A novel JAK inhibitor, peficitinib, demonstrates potent efficacy in a rat adjuvant-induced arthritis model
  Misato Ito, Shunji Yamazaki, Kaoru Yamagami, Masako Kuno, Yoshiaki Morita, Kenji Okuma, Koji Nakamura, Noboru Chida, Masamichi Inami, Takayuki Inoue, Shohei Shirakami, Yasuyuki Higashi
  Drug Discovery Research, Astellas Pharma Inc., Ibaraki, Japan
  Vol. 133, No.1, pp. 25-33 (2017)

第25回JPS優秀論文賞受賞論文プロフィール

The JPS Prize 2019 Awards

• Characterization and comparison of sodium-glucose cotransporter 2 inhibitors in pharmacokinetics, pharmacodynamics, and pharmacologic effects
  Atsuo Tahara, Toshiyuki Takasu, Masanori Yokono, Masakazu Imamura, Eiji Kurosaki
  Drug Discovery Research, Astellas Pharma Inc., Ibaraki, Japan
  Vol. 130, No.3, pp. 159-169 (2016)
• Rosmarinic acid inhibits inflammation and angiogenesis of hepatocellular carcinoma by suppression of NF-κB signaling in H22 tumor-bearing mice
  Wen Cao, Chao Hu, Lingling Wu, Liba Xu, Weizhe Jiang
  Department of Pharmacology, Guangxi Medical University, Nanning, Guangxi, 530021, China
  Vol. 132, No.2, pp. 131-137 (2016)

第24回JPS優秀論文賞受賞論文プロフィール

The JPS Prize 2018 Awards

• Glutamine protects against cisplatin-induced nephrotoxicity by decreasing cisplatin accumulation
  Hyun-Jung Kim, Dong Jun Park, Jin Hyun Kim, Eun Young Jeong, Myeong Hee Jung, Tae-Ho Kim, Jung Ill Yang, Gyeong-Won Lee, Hye Jin Chung , Se-Ho Chang
  Vol. 127, No. 1 pp. 117-126（2015）
• Involvement of TRPM2 in a wide range of inflammatory and neuropathic pain mouse models
  Kanako So, Kayo Haraguchi, Kayoko Asakura, Koichi Isami, Shinya Sakimoto, Hisashi Shirakawa, Yasuo Mori, Takayuki Nakagawa, Shuji Kaneko
  Vol. 127, No. 3 pp. 237-243 (2015)

第23回JPS優秀論文賞受賞論文プロフィール

The JPS Prize 2017 Awards

• Inhibition of Autophagy Contributes to Melatonin-Mediated Neuroprotection Against Transient Focal Cerebral Ischemia in Rats
  Yongqiu Zheng, Jincai Hou, Jianxun Liu, Mingjiang Yao, Lei Li, Bo Zhang, Hua Zhu, and Zhong Wang
  Vol. 124, No. 3 pp. 354-364（2014）
• Assessment of Testing Methods for Drug-Induced Repolarization Delay and Arrhythmias in an iPS Cell–Derived Cardiomyocyte Sheet: Multi-site Validation Study
  Yuji Nakamura, Junko Matsuo, Norimasa Miyamoto, Atsuko Ojima, Kentaro Ando, Yasunari Kanda, Kohei Sawada, Atsushi Sugiyama, and Yuko Sekino
  Vol. 124, No. 4 pp. 494-501 (2014)

第22回JPS優秀論文賞受賞論文プロフィール

The JPS Prize 2016 Awards

• Inhibition of Autophagy Enhances Sunitinib-Induced Cytotoxicity in Rat Pheochromocytoma PC12 cells
  Tatsuhiko Ikeda, Kiyo-aki Ishii, Yuria Saito, Masahiro Miura, Aoi Otagiri, Yasushi Kawakami, Hitoshi Shimano, Hisato Hara, Kazuhiro Takekoshi
  Vol. 121, No. 1 pp. 67-73（2013）
• Stimulation of Metabotropic Glutamate (mGlu) 2 Receptor and Blockade of mGlu1 Receptor Improve Social Memory Impairment Elicited by MK-801 in Rats
  Hirohiko Hikichi, Ayaka Kaku, Jun-ichi Karasawa, Shigeyuki Chaki
  Vol. 122, No. 1 pp. 10-16 (2013)

第21回JPS優秀論文賞受賞論文プロフィール

The JPS Prize 2015 Awards

• Tea Polyphenols Inhibit Rat Osteoclast Formation and Differentiation
  Yoshiomi Oka, Shinichi Iwai, Hitoshi Amano, Yuko Irie, Kentaro Yatomi, Kakei Ryu, Shoji Yamada, Katsunori Inagaki, Katsuji Oguchi
  Vol. 118, No. 1 pp. 55-64（2012）
• Nicotine- and Tar-Free Cigarette Smoke Induces Cell Damage Through Reactive Oxygen Species Newly Generated by PKC-Dependent Activation of NADPH Oxidase
  Hiroshi Asano, Takahiro Horinouchi, Yosuke Mai, Osamu Sawada, Shunsuke Fujii, Tadashi Nishiya, Masabumi Minami, Takahiro Katayama, Toshihiko Iwanaga, Koji Terada, Soichi Miwa
  Vol. 118, No. 2 pp. 275-287 (2012)
• Activation of ERK–p53 and ERK-Mediated Phosphorylation of Bcl-2 Are Involved in Autophagic Cell Death Induced by the c-Met Inhibitor SU11274 in Human Lung Cancer A549 Cells
  Ying Liu, Ying Yang, Yuan-Chao Ye, Qi-Feng Shi, Kuan Chai, Shin-ichi Tashiro, Satoshi Onodera, Takashi Ikejima
  Vol. 118 , No. 4 pp. 423-432 (2012)

第20回JPS優秀論文賞受賞論文プロフィール

The JPS Prize 2014 Awards

• Association Between Genetic Polymorphisms of the β1-Adrenergic Receptor and Sensitivity to Pain and Fentanyl in Patients Undergoing Painful Cosmetic Surgery
  Ayako Moriyama, Daisuke Nishizawa, Shinya Kasai, Junko Hasegawa, Ken-ichi Fukuda, Makoto Nagashima, Ryoji Katoh, and Kazutaka Ikeda
  Vol. 121, No. 1, pp. 48 – 57（2013）
• Volume Transmission of Substance P in Striatum Induced by Intraplantar Formalin Injection Attenuates Nociceptive Responses via Activation of the Neurokinin 1 Receptor
  Yoki Nakamura, Hiroki Izumi, Takumi Shimizu, Kazue Hisaoka-Nakashima, Norimitsu Morioka, and Yoshihiro Nakata
  Vol. 121, No. 4, pp. 257 – 271（2013）
• Significance of the Vascular Concentration of Angiotensin II―Receptor Blockers on the Mechanism of Lowering Blood Pressure in Spontaneously Hypertensive Rats
  Shinji Takai, Denan Jin, Hiroshi Sakonjo, Takayuki Takubo, and Toyofumi Nakanishi
  Vol. 123, No. 4, pp. 371 – 379（2013）

第19回JPS優秀論文賞受賞論文プロフィール

The JPS Prize 2013 Awards

• Expression of Microsomal Prostaglandin E Synthase-1 in the Spinal Cord in a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis
  Hiroko Miyagishi, Yasuhiro Kosuge, Kumiko Ishige, Yoshihisa Ito
  Vol. 118, No. 2, pp. 225 – 236（2012）
• Spinal Mechanism Underlying the Antiallodynic Effect of Gabapentin Studied in the Mouse Spinal Nerve Ligation Model
  Shin-ichi Morimoto, Masanori Ito, Satoko Oda, Atsushi Sugiyama, Masaru Kuroda, Satomi Adachi-Akahane
  Vol. 118, No. 4, pp. 455 – 466（2012）
• Synergism Between Interleukin (IL)-17 and Toll-like Receptor 2 and 4 Signals to Induce IL-8 Expression in Cystic Fibrosis Airway Epithelial Cells
  Shota Mizunoe, Tsuyoshi Shuto, Shingo Suzuki, Chizuru Matsumoto, Kenji Watanabe, Keiko Ueno-Shuto, Mary Ann Suico, Kouhei Onuki, Dieter C. G ruenert, Hirofumi Kai
  Vol. 118, No. 4, pp. 512 – 520（2012）

第18回JPS優秀論文賞受賞論文プロフィール

The JPS Prize 2012 Awards

• Bepridil Facilitates Early Termination of Spiral-Wave Reentry in Two-Dimensional Cardiac Muscle Through an Increase of Intercellular Electrical Coupling
  Hiroki Takanari, Haruo Honjo, Yoshio Takemoto, Tomoyuki Suzuki, Sara Kato, Masahide Harada, Yusuke Okuno, Takashi Ashihara, Tobias Opthof, Ichiro Sakuma, Kaichiro Kamiya and Itsuo Kodama
  J Pharmacol Sci. 2011 ; 115 : 15-26
• Dual Signaling Pathways of Arterial Constriction by Extracellular Uridine 5′-Triphosphate in the Rat
  Megumi Sugihara, Hiromitsu Morita, Miho Matsuda, Hisanori Umebayashi, Shunichi Kajioka, Shinichi Ito, Motohiro Nishida, Ryosuke Inoue, Toshiko Futatsuki, Jun Yamazaki, Yasuo Mori, Ryuji Inoue, Yushi Ito, Kihachiro Abe and Masato Hirata
  J Pharmacol Sci. 2011 ; 115 : 293-308
• Electrophysiological Characterization of Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells
  Masaki Honda, Jumpei Kiyokawa, Mitsuyasu Tabo and Tomoaki Inoue
  J Pharmacol Sci. 2011 ; 117 : 149-159

The JPS Prize 2011 Awards

• Mechanism Underlying the Protective Effect of Tempol and Nω-Nitro-L-arginine Methyl Ester on Acoustic Injury: Possible Involvement of c-Jun N-Terminal Kinase Pathway and Connexin26 in the Cochlear Spiral Ligament
  Reiko Nagashima, Taro Yamaguchi, Hajime Tanaka, and Kiyokazu Ogita
  J Pharmacol Sci. 2010 ; 114 : 50-62
• Computational Analysis of the Effects of Antineoplastic Agents on Axonal Transport
  Yoshio Goshima, Hiroshi Usui, Takahito Shiozawa, Tomonobu Hida, Satoshi Kuraoka, Sayumi Takeshita, Naoya Yamashita, Yasushi Ichikawa, Yoshinori Kamiya, Takahisa Gotoh, and Toshiyuki Gotoh
  J Pharmacol Sci. 2010 ; 114 : 168-179
• Antipsychotic Potential of Quinazoline ErbB1 Inhibitors in a Schizophrenia Model Established With Neonatal Hippocampal Lesioning
  Makoto Mizuno, Yuriko Iwakura, Masako Shibuya, Yingjun Zheng, Takeyoshi Eda, Taisuke Kato, Yohei Takasu, and Hiroyuki Nawa
  J Pharmacol Sci. 2010 ; 114 : 320-331

The JPS Prize 2010 Awards

• Involvement of Tryptase and Proteinase-Activated Receptor-2 in Spontaneous Itch-Associated Response in Mice With Atopy-like Dermatitis
  Kenichiro Tsujii, Tsugunobu Andoh, Haruna Ui, Jung-Bum Lee, and Yasushi Kuraishi
  J Pharmacol Sci. 2009 ; 109 : 388-395
• Predominant Promotion by Tacrolimus of Chondrogenic Differentiation to Proliferating Chondrocytes
  Yukari Nakamura, Takeshi Takarada, Ayumi Kodama, Eiichi Hinoi, and Yukio Yoneda
  J Pharmacol Sci. 2009 ; 109 : 413-423
• The C-Terminal Region of Serotonin Transporter Is Important for Its Trafficking and Glycosylation
  Mariko Nobukuni, Hideki Mochizuki, Satoshi Okada, Nobuhisa Kameyama, Anna Tanaka, Hikaru Yamamoto, Taku Amano, Takahiro Seki, and Norio Sakai
  J Pharmacol Sci. 2009 ; 111 : 392-404

The JPS Prize 2009 Awards

• Markedly Reduced White Adipose Tissue and Increased Insulin Sensitivity in Adcyap1-Deficient Mice
  Shuhei Tomimoto, Tatsuya Ojika, Norihito Shintani, Hitoshi Hashimoto, Ken-ichi Hamagami, Kazuya Ikeda, Masanori Nakata, Toshihiko Yada, Yusuke Sakurai, Takeshi Shimada, Yoshiko Morita, Chie Ishida, and Akemichi Baba
  J Pharmacol Sci. 2008 ; 107 : 41-48
• Long-Lasting Anti-emetic Effect of T-2328, a Novel NK₁ Antagonist
  Yumi Watanabe, Masahito Okamoto, Taketoshi Ishii, Satomi Takatsuka, Hiroyuki Taniguchi, Masaaki Nagasaki, and Akira Saito
  J Pharmacol Sci. 2008 ; 107 : 151-158
• µ-Opioid Receptor Forms a Functional Heterodimer With Cannabinoid CB₁ Receptor: Electrophysiological and FRET Assay Analysis
  Minoru Hojo, Yuka Sudo, Yuko Ando, Koichiro Minami, Masafumi Takada, Takehiro Matsubara, Masato Kanaide, Kohtaro Taniyama, Koji Sumikawa, and Yasuhito Uezono
  J Pharmacol Sci. 2008 ; 108 : 308-319

The JPS Prize 2008 Awards

• Blockade of Leukotriene B₄ Signaling Pathway Induces Apoptosis and Suppresses Cell Proliferation in Colon Cancer
  Aya Ihara, Koichiro Wada, Masato Yoneda, Nobutaka Fujisawa, Hirokazu Takahashi, and Atsushi Nakajima
  J Pharmacol Sci. 2007 ; 103 : 24-32
• Stimulation of Histamine 1 Receptor Up-Regulates Histamine H₁ Receptor Itself Through Activation of Receptor Gene Transcription
  Asish K. Das, Sachiho Yoshimura, Ryoko Mishima, Katsumi Fujimoto, Hiroyuki Mizuguchi, Shrabanti Dev, Yousuke Wakayama, Yoshiaki Kitamura, Shuhei Horio, Noriaki Takeda, and Hiroyuki Fukui
  J Pharmacol Sci. 2007 ; 103 : 374-382
• Membrane Stretch-Induced Activation of a TRPM4-Like Nonselective Cation Channel in Cerebral Artery Myocytes
  Hiromitsu Morita, Akira Honda, Ryuji Inoue, Yushi Ito, Kihachiro Abe, Mark T. Nelson, and Joseph E. Brayden
  J Pharmacol Sci. 2007 ; 103 : 417-426

The JPS Prize 2007 Awards

• Physiological Significance of Thromboxane A₂ Receptor Dimerization
  Masako Sasaki, Katsutoshi Miyosawa, Satoko Ohkubo and Norimichi Nakahata
  J Pharmacol Sci. 2006 ; 100 : 263-270
• Effects of Erythropoietin on Cardiac Remodeling After Myocardial Infarction
  Daisuke Nishiya, Takashi Omura, Kenei Shimada, Ryo Matsumoto, Takanori Kusuyama, Soichiro Enomoto, Hiroshi Iwao, Kazuhide Takeuchi, Junichi Yoshikawa and Minoru Yoshiyama
  J Pharmacol Sci. 2006 ; 101 : 31-39
• Heterotrimeric G Protein G_α13-Induced Induction of Cytokine mRNAs Through Two Distinct Pathways in Cardiac Fibroblasts
  Yuichi Nagamatsu, Motohiro Nishida, Naoya Onohara, Masashi Fukutomi, Yoshiko Maruyama, Hiroyuki Kobayashi, Yoji Sato and Hitoshi Kurose
  J Pharmacol Sci. 2006 ; 101 : 144-150

The JPS Prize 2006 Awards

• Increased Excretion of Urinary 20-HETE in Rats With Cyclosporine-Induced Nephrotoxicity
  Takayuki Seki, Tsuyoshi Ishimoto, Takanobu Sakurai, Yoshiko Yasuda, Kazuo Taniguchi, Mariko Doi, Mariko Sato, Richard J. Roman, and Noriyuki Miyata
  J Pharmacol Sci. 2005 ; 97 : 132-137
• Proteasome Inhibitors Protect Against Degeneration of Nigral Dopaminergic Neurons in Hemiparkinsonian Rats
  Masatoshi Inden, Jun-ichi Kondo, Yoshihisa Kitamura, Kazuyuki Takata, Kaneyasu Nishimura, Takashi Taniguchi, Hideyuki Sawada, and Shun Shimohama
  J Pharmacol Sci. 2005 ; 97 : 203-211

The JPS Prize 2005 Awards

• A Novel Method to Quantify Calcium Response Pattern and Oscillation Using Fura2 and Acridine Orange
  Mitsuhiro Morita, Jinichi Susuki, Takanori Moto, Chitose Higuchi, and Yoshihisa Kudo
  J Pharmacol Sci. 2004 ; 94 : 25 – 30
• Involvement of TRPM7 in Cell Growth as a Spontaneously Activated Ca2+ Entry Pathway in Human Retinoblastoma Cells
  Toyohisa Hanano, Yuji Hara, Juan Shi, Hiromitsu Morita, Chisato Umebayashi, Emiko Mori, Hideki Sumimoto, Yushi Ito, Yasuo Mori, and Ryuji Inoue
  J Pharmacol Sci. 2004 ; 95 : 403 – 419
• Angiogenesis In Vitro: Vascular Tube Formation From the Differentiation of Neural Stem Cells
  Kazuhiko Oishi, Akiko Kobayashi, Katsunori Fujii, Daisuke Kanehira, Yuko Ito, and Masaatsu K. Uchida
  J Pharmacol Sci. 2004 ; 96 : 208 – 218

The JPS Prize 2004 Awards

• Utilization of Knockout Mice to Examine the Potential Role of Gastric Histamine H2- Receptors in Menetrier’s Disease
  Toshiki Ogawa, Kazuhiko Maeda, Shunsuke Tonai, Takashi Kobayashi, Takeshi Watanabe, and Susumu Okabe
  J Pharmacol Sci. 2003；91：61－70.
• Orexin Receptor Type-1 Couples Exclusively to Pertussis Toxin-Insensitive G-Proteins, While Orexin Receptor Type-2 Couples to Both Pertussis Toxin-Sensitive and -Insensitive G-Proteins
  Yun Zhu，Yoshihiro Miwa, Akihiro Yamanaka, Toshihiko Yada, Megumi　Shibahara, Yoichiro Abe, Takeshi Sakurai, and Katsutoshi Goto
  J Pharmacol Sci. 2003；92：259－266.
• Evaluation of Human Peroxisome Proliferator-Activated Receptor(PPAR) Subtype Selectivityof a Variety of Anti-inflammatory Drugs Based on a Novel Assay for PPARδ(β)
  Hitoshi Kojo, Masao Fukagawa, Kaoru Tajima, Akiko Suzuki, Takao Fujimura, Ichiro Aramori, Ken-ichi Hayashi, and Shintaro Nishimura
  J Pharmacol Sci. 2003；93：347-355.

The JJP Prize 2003 Awards

• Novel Mutations in C-terminal Channel Region of the Ryanodine Receptor in Malignant Hyperthermia Patients
  Hideto Oyamada, Keiko Oguchi, Naoto Saitoh*, Toshiko Yamazawa, Kenzo Hirose, Yoko Kawana, Kazunao Wakatsuki, Katsuji Oguchi, Megumi Tagami, Kazuo Hanaoka, Makoto Endo and Masamitsu Iino
  Jpn. J. Pharmacol. 88, 159-166 (2002)
  *The first three authors equally contributed to this work.
• Contractile Responses and Myosin Phosphorylation in Reconstituted Fibers of Smooth Muscle Cells From the Rat Cerebral Artery
  Kazuhiko Oishi, Yoshitaka Takatoh, Jianjun Bao and Masaatsu K. Uchida
  Jpn. J. Pharmacol. 90, 36-50 (2002)

The JJP Prize 2002 Awards

• Molecular Mechanisms for a2-Adrenoceptor-Mediated Regulation of Synoviocyte Population
  Katsuyuki Mishima, Hitomi Otani, Takatoshi Tanabe, Hiroshi Kawasaki, Akihiro Oshiro, Naoaki Saito, Ryokei Ogawa and Chiyoko Inagaki
  Jpn. J. Pharmacol. 85, 214 – 226 (2001)
• Ca²⁺-Images of Smooth Muscle Cells and Endothelial Cells in One Confocal Plane in Femoral Artery Segments of the Rat
  Yoshiaki Ohi, Nobuhiko Takai, Katsuhiko Muraki, Minoru Watanabe and Yuji Imaizumi
  Jpn. J. Pharmacol. 86, 106 – 113 (2001)
• Adenylate Cyclase / Protein Kinase A Signaling Pathway Enhances Angiogenesis Through Induction of Vascular Endothelial Growth Factor In Vivo
  Hideki Amano, Kao Ando, Satoshi Minamida, Izumi Hayashi, Michiko Ogino, Shohei Yamashina, Hirokuni Yoshimura and Masataka Majima
  Jpn. J. Pharmacol. 87, 181 – 188 (2001)

The JJP Prize 2001 Awards

• Endomorphin-1 Discriminates the m-Opioid Receptor From the d- and k-Opioid Receptors by Recognizing the Difference in Multiple Regions
  Soichiro Ide, Kyoko Sakano, Takahiro Seki, Shinichiro Awamura, Masabumi Minami and Masamichi Satoh
  Jpn. J. Pharmacol. 83, 306 – 311 (2000)
• Pharmacological and Immunohistochemical Characterization of a Mouse Model of Acute Herpetic Pain
  Ichiro Takasaki, Tsugunobu Andoh, Makoto Nitta, Hiroki Takahata, Hideo Nemoto, Kimiyasu Shiraki, Hiroshi Nojima and Ysasushi Kuraishi
  Jpn. J. Pharmacol. 83, 319 – 326 (2000)
• Calcium Signaling and c-Fos Gene Expression via M3 Muscarinic Acetylcholine Receptors in Human T- and B-Cells
  Takeshi Fujii and Koichiro Kawashima
  Jpn. J. Pharmacol. 84, 124 – 132 (2000)

The JJP Prize 2000 Awards

• Long-Term Treatment With Angiotensin Converting Enzyme Inhibitor Restores Reduced Calcitonin Gene-Related Peptide-Containing Vasodilator Nerve Function in Mesenteric Artery of Spontaneously Hypertensive Rats
  Hiromu Kawasaki, Masatoshi Okazaki, Akira Nakatsuma, Yuichi Mimaki, Hiroaki Araki and Yutaka Gomita
  Jpn. J. Pharmacol. 79, 221 – 229 (1999)
• Propofol Inhibits Muscarinic Acetylcholine Receptor-Mediated Signal Transduction in Xenopus Oocytes Expressing the Rat M1 Receptor
  Yoshihisa Nagase, Muneshige Kaibara, Yasuhito Uezono, Futoshi Izumi, Koji Sumikawa and Kohtaro Taniyama
  Jpn. J. Pharmacol. 79, 319 – 325 (1999)
• Natriuretic Peptide Receptors, NPR-A and NPR-B, in Cultured Rabbit Retinal Pigment Epithelium Cells
  Yoshito Fujiseki, Kyoko Omori, Koichiro Omori, Yoshito Mikami, Junko Suzukawa, Gaku Okugawa, Masanobu Uyama and Chiyoko Inagaki
  Jpn. J. Pharmacol. 79, 359 – 368 (1999)

The JJP Prize 1999 Awards

• Vascular alpha1-Adrenoceptor Subtype Selectivity and alpha1-Blocker Induced Orthostatic Hypotension
  Hitoshi Take, Katsushi Shibata, Takeo Awaji, Akira Hirasawa, Ichiro Ikegaki, Toshio Asano, Tatsuyuki Takada and Gozoh Tsujimoto
  Jpn. J. Pharmacol. 77, 61-70 (1998)
• Co-culture With the Striatum Attenuates N-Methyl-D-aspartate Cytotoxicity in Dopaminergic Neurons of Rat Mesencephalic Slice Cultures
  Takehiko Maeda, Masakazu Ibi, Seiichiro Shimazu and Akinori Akaike
  Jpn. J. Pharmacol. 77, 161-167 (1998)
• Protective Effect of Talipexole on MPTP-Treated Planarian, a Unique Parkinsonian Worm Model
  Yoshihisa Kitamura, Jun-ichi Kakimura and Takashi Taniguchi
  Jpn. J. Pharmacol. 78, 23-29 (1998)

The JJP Prize 1998 Awards

• Role of Endogenous Basic Fibroblast Growth Factor in the Healing of Gastric Ulcers in Rats
  Hiroshi Satoh, Akio Shino, Fumihiko Sato, Shoichi Asano, Izumi Murakami, Nobuhiro Inatomi, Hideaki Nagaya, Koichi Kato, Sandor Szabo and Judah Folkman
  Jpn. J. Pharmacol. 73, 59-71 (1997)
• Significant Roles of Inducible Cyclooxygenase (COX)-2 in Angiogenesis in Rat Sponge Implants
  Masataka Majima, Masako Isono, Yasuhiro Ikeda, Izumi Hayashi, Ko Hatanaka, Yoshiteru Harada, Osamu Katsumata, Shohei Yamashina, Makoto Katori and Shouzo Yamamoto
  Jpn. J. Pharmacol. 75, 105-114 (1997)
• Basic Fibroblast Growth Factor and Brain-Derived Neurotrophic Factor Promote Survival and Neuronal Circuit Formation in Organotypic Hippocampal Culture
  Yasuhiro Nakagami, Hiroshi Saito and Norio Matsuki
  Jpn. J. Pharmacol. 75, 319-326 (1997)

The JJP Prize 1997 Awards

• Restricted Propagation of Cytoplasmic Ca2+ Oscillation into the Nucleus in Guinea Pig Cardiac Myocytes as Revealed by Rapid Scanning Confocal Microscopy and Indo-1
  Hikaru Tanaka, Toru Kawanishi, Yoshimitsu Kato, Ryu Nakamura and Koki Shigenobu
  Jpn. J. Pharmacol. 70, 235-242 (1996)
• Effects of Stilbene Derivatives SITS and DIDS on Development of Intracellular Acidosis during Ischemia in Isolated Guinea Pig Ventricular Papillary Muscle In Vitro
  Zhong-Fang Lai, Jie Liu and Katsuhide Nishi
  Jpn. J. Pharmacol. 72, 161-174 (1996)
• Electrophysiological and Pharmacological Characteristics of Ionotropic
  Glutamate Receptors in Medial Vestibular Nucleus Neurons:
  A Whole Cell Patch Clamp Study in Acutely Dissociated Neurons
  Norio Sakai, Hisamitsu Ujihara, Kumatoshi Ishihara, Masashi Sasa and Chikako Tanaka
  Jpn. J. Pharmacol. 72, 335-346 (1996)

The JJP Prize 1996 Awards

• Adrenergic Receptor-Mediated Cl- Transport in Rabbit Corneal Endothelial Cells
  Tohru Yasukura, Masafumi Inoue, Takao Irie, Mitsuyoshi Hara, Yoshito Mikami, Xun-ting Zeng, Toshiko Mikami, Kyoko Omori, Akio Minato, Masanobu Uyama and Chiyoko Inagaki
  Jpn. J. Pharmacol. 67, 315-320 (1995)
• Calcitonin Gene-Related Peptide Mediated Neurogenic Vasorelaxation in the Isolated Canine Lingual Artery
  Dai Kobayashi, Kazuo Todoki, Satoru Ozono and Eiichiro Okabe
  Jpn. J. Pharmacol. 67, 329-339 (1995)
• Mechanism and Properties of Inhibition of Purified Rat Brain Adenylate Cyclase by G Protein beta-gamma-Subunits
  Keiichi Enomoto, Masako Takano, Shunji Ariyoshi and Takeo Asakawa
  Jpn. J. Pharmacol. 69, 239-250 (1995)